个人简介

2020.12- 至今     上海交通大学，必威，长聘教轨副教授

2017.01- 2020.12，美国密歇根州立大学，助理研究员/研究助理教授

2014.08- 2016.12，美国爱荷华州立大学，博士后
       2008.09- 2014.06，中科院植物生理生态研究所，博士
       2004.09- 2008.06，华中农业大学，学士

研究领域

1，细胞自噬在调控植物抗逆与生长中的作用机制；
       2，精细调控内质网胁迫信号以平衡植物抗逆与生长；
       3，叶绿体及其相关代谢途径对植物抗逆、营养与产量的影响。

主要成果

1，发现植物中首个直接负调控细胞自噬的关键因子COST1并揭示其分子机制(2020，PNAS；2020，Autophagy)；
       2，证明内源本底水平内质网胁迫信号的激活对植物正常生长和发育是必需的(2019，Plant Physiology)；
       3，阐明植物内质网胁迫诱导的细胞自噬是由IRE1介导的RIDD途经来调控(2018，Autophagy)。

主要论文(^#co-first, *corresponding)

1. Bao Y*, Bassham DC* (2020) ER-Phagy and its role in ER homeostasis in plants. Plants. 9 (12), 1771
2. Yu X*, Bao Y* (2020) Phylogenetics of molecular regulators contributing to plant stress tolerance. Diversity. 12(10), 407
3. Bao Y*, Magallenes-Lundback M, Deason N, DellaPenna D* (2020) High throughput profiling of tocochromanols in leaves and seeds of Arabidopsis and Maize. Plant Methods. 16 (1), 1-14
4. Bao Y* (2020) Links between drought stress and autophagy in plants. Plant Signaling & Behavior. 15 (8), 1779487
5. Bao Y*, Bassham DC* (2020) COST1 balances plant growth and stress tolerance via attenuation of autophagy. Autophagy. 16 (6), 1157-1158
6. Bao Y^#, *, Song WM^#, Wang PP, Yu X, Li B, Jiang CM, Shiu SH, Zhang HX*, and Bassham DC* (2020) COST1 regulates autophagy to control plant drought tolerance. PNAS. 117 (13), 7482-7493 (Recommended by F1000Prime/Faculty Opinions; highlighted by Plantae)
7. Song WM, Cheng ZH, Guo XT, Yu CY, Wang HH, Wang J, Zhang HX*, Bao Y* (2019) Overexpression of NHL6 affects seed production in transgenic Arabidopsis plants. Plant Growth Regulation. 88 (1), 41-47
8. Bao Y, Bassham DC, Howell SH* (2019) A functional unfolded protein response is required for normal vegetative development in Arabidopsis. Plant Physiology. 179 (4), 1834-1843 (Highlighted by Plantae)
9. Bao Y*, Bassham DC* (2018) Using Arabidopsis protoplasts to study unfolded protein response signaling. Bio-protocol. https://bio-protocol.org/e3101
10. Bao Y, Pu YT, Yu X, Gregory BD, Srivastava R, Howell SH, Bassham DC* (2018) IRE1b degrades RNAs encoding proteins that interfere with the induction of autophagy by ER stress. Autophagy. 14 (9), 1562-1573
11. Bao Y, Howell SH* (2017) The Unfolded Protein Response Supports Plant Development and Defense as well as Responses to Abiotic Stress. Frontiers in Plant Science. 8, 344
12. Bao Y, Mugume Y, Bassham DC* (2017) Biochemical methods to monitor autophagic responses in plants. Methods in Enzymology. 588:497-513
13. Bao Y, Song WM, Zhang HX* (2016) Role of Arabidopsis NHL family in ABA and stress response. Plant Signaling & Behavior. 11 (5), e1180493
14. Bao Y^#, Song WM^#, Pan J, Jiang CM, Srivastava R, Li B, Zhu LY, Su HY, Gao XS, Liu H, Yu X, Yang L, Cheng XH, Zhang HX* (2016) Overexpression of the NDR1/HIN1-like gene NHL6 modifies abscisic acid sensitivity and biosynthesis in Arabidopsis. Plos One. 11 (2), e0148572
15. Bao Y, Song WM, Jin YL, Jiang CM, Yang Y, Li B, Huang WJ, Liu H, Zhang HX* (2014) Characterization of Arabidopsis Tubby-like proteins and redundant function of AtTLP3 and AtTLP9 in plant response to ABA and osmotic stress. Plant Molecular Biology. 86:471-483
16. Bao Y, Wang CT, Jiang CM, Pan J, Zhang GB, Liu H, Zhang HX* (2014) The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis. New Phytologist. 202: 174-187

合作论文

1. Kang T, Yu CY, Liu Y, Song WM, Bao Y, Guo XT, Li B and Zhang HX (2019) Subtly manipulated expression of ZmmiR156 in tobacco improves drought and salt tolerance without changing the architecture of transgenic plants. Frontiers in Plant Science. 10, 1664
2. Wang HH, Wang XQ, Song WM, Bao Y, Jin YL, Jiang CM, Wang CT, Li B and Zhang HX (2019) PdMYB118, isolated from a red leaf mutant of Populus deltoids, is a new transcription factor regulating anthocyanin biosynthesis in poplar. Plant Cell Report. 38 (8), 927-936
3. Zhu MM, Liu EQ, Bao Y, Duan SL, She J, Liu H, Wu TT, Cao XQ, Zhang J, Li B, Sheng YT, Liang MX, Zhang HX, Guo XT (2018) Low concentration of corn steep liquor promotes seed germination, plant growth, biomass production and flowering in soybean. Plant Growth Regulation. 87 (1), 29-37
4. Jin YL, Tang RJ, Wang HH, Jiang CM, Bao Y, Yang Y, Liang MX, Kong FJ, Li B, Zhang HX (2017). Overexpression of Populus trichocarpa CYP85A3 promotes growth and biomass production in transgenic trees. Plant Biotechnology Journal. 15: 1309-1321
5. Deng Y, Srivastava R, Quilichini TD, Dong HL, Bao Y, Horner HT, Howell SH (2016) IRE1, a component of the Unfolded Protein Response signaling pathway, protects pollen development in Arabidopsis from heat stress. Plant Journal. 88: 193-204
6. Yang Y, Tang RJ, Li B, Wang HH, Jin YL, Jiang CM, Bao Y, Su HY, Zhao N, Ma XJ, Yang L, Chen SL, Cheng XH, Zhang HX (2015) Overexpression of a Populus trichocarpa H+-pyrophosphatase gene PtVP1.1 confers salt tolerance on transgenic poplar. Tree Physiology. 35: 663-677
7. Wang CT, Bao Y, Wang QQ, Zhang HX (2013) Introduction of the rice CYP714D1 gene into Populus inhibits expression of its homologous genes and promotes growth, biomass production and xylem fibre length in transgenic trees. Journal of Experimental Botany. 64: 2847-57
8. Tang RJ, Liu H, Bao Y, Lv QD, Yang L, Zhang HX (2010) The woody plant poplar has a functionally conserved salt overly sensitive pathway in response to salinity stress. Plant Molecular Biology. 74: 367-380

发明专利

1. Zhang HX, Bao Y, Wang CT. (2013) Plant drought resistance ability improving method. CN104278053A
2. Bao Y, Song WM, Zhang HX. (2018) Enhance plant drought resistance by inhibiting the expression of a COST1 gene. CN108949821A
3. Bao Y, Song WM, Zhang HX. (2020) Method by inhibiting the expression of COST1 gene to improve plant drought resistance. PCT Priority to CN201810901473.7A

实验室招聘

       欢迎报考本课题组的硕/博研究生；诚邀优秀博士后加盟从事合作研究；特别欢迎本科生同学加入开展科研训练。