吕东平 职       称：教授  研究方向：植物天然免疫；水稻稻瘟菌分子互作 电子信箱：dplu@sjtu.edu.cn

 

个人简历:

1998年7月毕业于内蒙古大学生命科学学院，获学士学位；2001年7月获中国科学院植物研究所硕士学位；2007年12月获美国夏威夷大学分子生物学与生物工程学获博士学位；2008/2-2008/10，美国夏威夷大学海洋系（海洋生物学专业），博士后；2009/2-2012/9，美国Texas A&M 大学生物化学与生物物理系，博士后/助理研究科学家；2012/10-2022/10，中科院遗传发育所农业资源中心，研究员，植物遗传与育种研究室副主任、主任，河北省作物学会副理事长；2022/11-至今，必威，教授。曾入选国家海外青年人才项目（2012年），并获得基金委“优秀青年基金”资助（2013年）。Journal of Integrative Agriculture 杂志编委。

 

代表论文：

1. Liu X, Zhou Y, Chen K, Xiao Z, Liang X, Lu D*. (2022) Phosphorylation status of CPK28 affects its ubiquitination and protein stability. New Phytol. doi:10.1111/nph.18596.

2. Zou Y, Liu Z, Bai J, Zhou Y, Lu D*. (2022) Mitochondrial proteotoxic stresses activate abscisic acid signaling in plants. Environ Exp Bot. Doi:10.1016/j.envexpbot.2022.105134

3. Liu X, Zhou Y, Du M, Liang X, Fan F, Huang G, Zou Y, Bai J, Lu D*. (2022) The calcium-dependent protein kinase CPK28 is targeted by the ubiquitin ligases ATL31 and ATL6 for proteasome-mediated degradation to fine-tune immune signaling in Arabidopsis. Plant Cell. 34(1):679-697. 

4. Bai J, Huang G, Chen K, Wang R, Lu D*. (2022) A receptor-like cytoplasmic kinase PCRK2 undergoes ubiquitination and proteasomal degradation. Biochem Biophys Res Commun. 587:113-118. 

5. Zhou Y, Fan F, Han Y, Lu D*. (2022) Arabidopsis PDI11 interacts with lectin molecular chaperons calreticulin 1 and 2 through its D domain. Biochem Biophys Res Commun. 588:55-60. 

6. Fan F, Zhang Q, Zhang Y, Huang G, Liang X, Wang CC, Wang L, Lu D*. (2022) Two protein disulfide isomerase subgroups work synergistically in catalyzing oxidative protein folding. Plant Physiol. 188(1):241-254. 

7. Zou Y, Wang S, Lu D*. (2020) MiR172b-TOE1/2 module regulates plant innate immunity in an age-dependent manner. Biochem Biophys Res Commun. 531(4):503-507.

8. Fan F, Zhang Q, Lu D*. (2020) Identification of N-glycosylation sites on AtERO1 and AtERO2 using a transient expression system. Biochem Biophys Res Commun. 533(3):481-485.

9. Fan F, Zhang Y, Huang G, Zhang Q, Wang CC, Wang L, Lu D* (2019) AtERO1 and AtERO2 exhibit differences in catalyzing oxidative protein folding in the ER. Plant Physiol. 180(4):2022-2033.

10. Huang G, Sun J, Bai J, Han Y, Fan F, Wang S, Zhang Y, Zou Y, Han Z, Lu D*. (2019) Identification of critical Cysteine sites in brassinosteroid-insensitive 1 and novel signaling regulators using a transient expression system. New Phytol. 222(3):1405-1419.

11. Zou Y, Wang S, Zhou Y, Bai J, Huang G, Liu X, Zhang Y, Tang D, Lu D*. (2018) Transcriptional Regulation of the Immune Receptor FLS2 Controls the Ontogeny of Plant Innate Immunity. Plant Cell. 30(11):2779-2794.

12. Sun J, Huang G, Fan F, Wang S, Zhang Y, Han Y, Zou Y, Lu D*. (2017) Comparative study of Arabidopsis PBS1 and a wheat PBS1 homolog helps understand the mechanism of PBS1 functioning in innate immunity. Sci Rep. 7(1):5487.

13. Han Y, Sun J, Yang J, Tan Z, Luo J, Lu D*. (2017) Reconstitution of the plant ubiquitination cascade in bacteria using a synthetic biology approach. Plant J. 91(4): 766-776.

Faculty 1000（https://f1000.com/prime/727618151）

14. Wang S, Sun J, Fan F, Tan Z, Zou Y, Lu D*. (2016) A Xanthomonas oryzae pv. oryzae effector, XopR, associates with receptor-like cytoplasmic kinases and suppresses PAMP-triggered stomatal closure. Sci China Life Sci. 59(9):897-905.

15. Li B*, Lu D*, Shan L. (2014) Ubiquitination of pattern recognition receptors in plant  innate immunity. Mol Plant Pathol. 15(7):737-746. (*equal contributors).

16. Lu D, Lin W, Gao X, Wu S, Cheng C, Avila J, Heese A, Devarenne TP, He P, Shan L. (2011) Direct ubiquitination of pattern recognition receptor FLS2 attenuates plant innate immunity. Science, 332(6036):1439-1442.

17. Lu D*, Wu S*, Gao X, Zhang Y, Shan L, He P. (2010) A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity. Proc Natl Acad Sci USA. 107(1):496-501. (*equal contributors).

 

授权专利:

吕东平等，水稻抗稻瘟病基因Pisj及其应用，中国，ZL 2018 1 0946094. X. 专利公开日，2021年8月20日。